BDBM50512442 CHEMBL4554856

SMILES CC(C)N1Cc2cc(O[C@@H](C)CNC(=O)c3cnn4cc1cnc34)cc(F)c2Cl

InChI Key InChIKey=JHUWBOAVDAIILQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50512442   

TargetHigh affinity nerve growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50512442(CHEMBL4554856)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant full length human TRKA expressed in U2OS cells using Poly(Glu:Tyr) as substrate after 30 mins by scintillation counting ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50512442(CHEMBL4554856)
Affinity DataIC50: 0.536nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50512442(CHEMBL4554856)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of TRKB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed