BDBM50512454 CHEMBL4459162

SMILES CC(C)(O)c1ccc2nc(c(NC(=O)c3cc(-c4ncccn4)c(cc3F)C(F)(F)F)n2c1)-c1ccccc1

InChI Key InChIKey=LOIOLKANEMTMSV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50512454   

TargetHigh affinity nerve growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50512454(CHEMBL4459162)
Affinity DataIC50: 0.890nMAssay Description:Inhibition of recombinant full length human TRKA expressed in U2OS cells using Poly(Glu:Tyr) as substrate after 30 mins by scintillation counting ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed