BDBM50512504 CHEMBL4540580

SMILES OC(=O)c1ccc(cc1)-n1nc(C(=O)c2c(Cl)cccc2Cl)c2ccccc12

InChI Key InChIKey=GVWQZVAMODQAFX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512504   

TargetNuclear receptor ROR-gamma(Human)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50512504(CHEMBL4540580)
Affinity DataIC50: 3.80nMAssay Description:Inverse agonist activity at GST-tagged RORgammat LBD (unknown origin) using fluorescein-D22 co-activator peptide as substrate incubated for 1 hr by T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50512504(CHEMBL4540580)
Affinity DataIC50: 29nMAssay Description:Transactivation of recombinant GAL4-DBD fused RORgammat LBD (unknown origin) expressed in HEK293T cells incubated for 18 to 24 hrs by dual-Glo lucife...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed