BDBM50512506 CHEMBL4551954

SMILES Cc1cccc2c(cn(-c3ccc(cc3F)C(O)=O)c12)C(=O)c1ccccc1Cl

InChI Key InChIKey=RBPHCNCKGJRVLB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512506   

TargetNuclear receptor ROR-gamma(Human)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50512506(CHEMBL4551954)
Affinity DataIC50: 8.10nMAssay Description:Inverse agonist activity at GST-tagged RORgammat LBD (unknown origin) using fluorescein-D22 co-activator peptide as substrate incubated for 1 hr by T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50512506(CHEMBL4551954)
Affinity DataIC50: 119nMAssay Description:Transactivation of recombinant GAL4-DBD fused RORgammat LBD (unknown origin) expressed in HEK293T cells incubated for 18 to 24 hrs by dual-Glo lucife...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed