BDBM50512579 CHEMBL4442828

SMILES Cn1c(cc2c(Cl)c(Cl)ccc12)C(=O)NC1(COC1)c1ccc(CO)cc1

InChI Key InChIKey=SOTJPDGLCOSZOR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50512579   

TargetD-3-phosphoglycerate dehydrogenase(Human)
Meyer Cancer Center

Curated by ChEMBL
LigandPNGBDBM50512579(CHEMBL4442828)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of PHGDH (unknown origin) using 140 nM of PHGDH and 3-PG as substrate incubated for 20 mins in presence of NAD+, PSAT1, PSPH by diaphorase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed