BDBM50512906 CHEMBL4538822

SMILES Fc1ccccc1N1CCN(Cc2csc(n2)-c2ccc3OCOc3c2)CC1

InChI Key InChIKey=CIXGFQNLXZKQAX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512906   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Rheinische Friedrich-Wilhelms-University of Bonn

Curated by ChEMBL
LigandPNGBDBM50512906(CHEMBL4538822)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in MDCK2 cells co-expressing BCRP (unknown origin) assessed as effect on pheophorbide A accumulation p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Rheinische Friedrich-Wilhelms-University of Bonn

Curated by ChEMBL
LigandPNGBDBM50512906(CHEMBL4538822)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of ABCB1 in human A2780/ADR cells preincubated for 30 mins followed by calcein AM addition and measured at 60 secs time interval by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed