BDBM50512924 CHEMBL4516184

SMILES O=C(NCCc1ccccn1)[C@@H]1CCCC[C@H]1C(=O)c1ccc(cc1)-c1cc[nH]n1

InChI Key InChIKey=CJHPFFSSMGEXHF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512924   

LigandPNGBDBM50512924(CHEMBL4516184)
Affinity DataIC50: 251nMAssay Description:Inhibition of [3H]MK0591 binding to human FLAP expressed in human COS7 cell membranes measured after 60 to 80 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
LigandPNGBDBM50512924(CHEMBL4516184)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of FLAP in human whole blood assessed as reduction in calcium ionophore-stimulated LTB4 production preincubated for 30 mins followed by ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed