BDBM50513072 CHEMBL4574883
SMILES Fc1cccc(c1)-n1c(nn2ccc(Cl)c2c1=O)[C@@H]1CCCN1c1ncnc2[nH]cnc12
InChI Key InChIKey=VSYBLIHWVCIUHC-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50513072
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hutchison Medipharma
Curated by ChEMBL
Hutchison Medipharma
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in antihuman IgM-stimulated AKT phosphorylation at Ser473 residue preincubated for...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hutchison Medipharma
Curated by ChEMBL
Hutchison Medipharma
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Hutchison Medipharma
Curated by ChEMBL
Hutchison Medipharma
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human full-length His-tagged PI3K p110gamma expressed in baculovirus expression system using PIP2 as substrate measured aft...More data for this Ligand-Target Pair