BDBM50513200 CHEMBL4514512

SMILES COc1cc2CC(=O)N([C@@H](c3ccccc3)c2cc1OC(C)C)c1ccc(cc1)N(C)C[C@H]1CC[C@@H](CC1)N1CCN(C)C(=O)C1

InChI Key InChIKey=AJMDTIJPYVWRLO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50513200   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50513200(CHEMBL4514512)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of p53 protein binding to MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50513200(CHEMBL4514512)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of MDMX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed