BDBM50513201 CHEMBL4447592

SMILES CC(C)(C)NC(=O)[C@@H](c1c2ccc(cc2[nH]c1C(=O)O)Cl)N(Cc3ccc(cc3)OCc4ccc(cc4)Cl)C=O

InChI Key InChIKey=PESUUIPTWNTJKA-UHFFFAOYSA-N

Data  1 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50513201   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50513201(CHEMBL4447592)
Affinity DataIC50: 600nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50513201(CHEMBL4447592)
Affinity DataKi:  600nMAssay Description:Inhibition of p53 protein binding to MDM2 (unknown origin) by western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)