BDBM50513205 CHEMBL4437666

SMILES Fc1cccc(F)c1N[C@@]1(Cc2cccc(Cl)c2)C(=O)Nc2cc(Cl)ccc12

InChI Key InChIKey=FUFYOQRYQLCEGB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50513205   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50513205(CHEMBL4437666)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50513205(CHEMBL4437666)
Affinity DataKi:  1.20nMAssay Description:Inhibition of p53 protein binding to MDM2 (unknown origin) by western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed