BDBM50513206 CHEMBL4546186

SMILES CC(C)C[C@H](N[C@H](C(=O)NCc1ccccc1)c1c([nH]c2cc(Cl)ccc12)C(=O)NO)C(=O)NO

InChI Key InChIKey=VRQFWSWBTGHUMK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50513206   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50513206(CHEMBL4546186)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50513206(CHEMBL4546186)
Affinity DataKi:  1.20nMAssay Description:Inhibition of p53 protein binding to MDM2 (unknown origin) by western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed