BDBM50513460 CHEMBL4443898

SMILES O\N=C(/Nc1ccc(F)c(Br)c1)c1nonc1NCCN1CCN(CCN2CCOCC2)S1(=O)=O

InChI Key InChIKey=WFLHTSBRAXUAJW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50513460   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50513460(CHEMBL4443898)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human IDO1 expressed in HEK293 cells assessed as N-formylkynurenine formation by measuring kynurenine level incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50513460(CHEMBL4443898)
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli BL21 cells using L-tryptophan as substrate incubated for 30 mins by methylene blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed