BDBM50513891 CHEMBL4435875

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

InChI Key InChIKey=QBPBVXUXPKMQFE-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50513891   

TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513891(CHEMBL4435875)
Affinity DataKi:  300nMAssay Description:Inhibition of Dengue virus serotype 1 NS2B-NS3 protease preincubated for 20 mins followed by Abz-RRRRSAG-nY-NH2 addition and measured for 60 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513891(CHEMBL4435875)
Affinity DataKi:  400nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease preincubated for 20 mins followed by Abz-RRRRSAG-nY-NH2 addition and measured for 60 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513891(CHEMBL4435875)
Affinity DataKi:  700nMAssay Description:Inhibition of Dengue virus serotype 3 NS2B-NS3 protease preincubated for 20 mins followed by Abz-RRRRSAG-nY-NH2 addition and measured for 60 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGenome polyprotein(DENV-2)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50513891(CHEMBL4435875)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of Dengue virus serotype 4 NS2B-NS3 protease preincubated for 20 mins followed by Abz-RRRRSAG-nY-NH2 addition and measured for 60 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed