BDBM50513941 CHEMBL4519186

SMILES CCNC1=N[C@@H]2[C@@H](OC)[C@H](O)[C@@H](CO)O[C@@H]2S1

InChI Key InChIKey=JRZSXVZVOPYSIU-UHFFFAOYSA-N

Data  2 KI  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50513941   

TargetProtein O-GlcNAcase(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50513941BDBM50513941(CHEMBL4519186)
Affinity DataKi:  270nMAssay Description:Inhibition of recombinant human OGAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetBeta-hexosaminidase subunit beta(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50513941BDBM50513941(CHEMBL4519186)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human beta hexosaminidase assessed as inhibitory constant using 4-methylumbelliferyl N-acetyl-beta-D-glucosaminide dihydrate as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50513941BDBM50513941(CHEMBL4519186)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Cav1.2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50513941BDBM50513941(CHEMBL4519186)
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of PXR (unknown origin) assessed as CYP3A4 inductionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50513941BDBM50513941(CHEMBL4519186)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50513941BDBM50513941(CHEMBL4519186)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of MK-0499 from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50513941BDBM50513941(CHEMBL4519186)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50513941BDBM50513941(CHEMBL4519186)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50513941BDBM50513941(CHEMBL4519186)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed