BDBM50514133 CHEMBL4517952

SMILES Fc1cccc(Cl)c1C(=O)Nc1ccc(Oc2cc(Cl)cc(c2)C(F)(F)F)cc1

InChI Key InChIKey=FODKZKBHVQZXLE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50514133   

TargetToll-like receptor 8(Human)
University of Colorado Boulder

Curated by ChEMBL
LigandPNGBDBM50514133(CHEMBL4517952)
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK293 cells assessed as reduction in R848-induced NFkappaB production incubated for 16 hrs by quanti-blue SEAP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed