BDBM50514137 CHEMBL4455524

SMILES Fc1ccc(Cl)cc1C(=O)Nc1ccc(Oc2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1

InChI Key InChIKey=SGCLBPLKZIPAKQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50514137   

TargetToll-like receptor 8(Human)
University of Colorado Boulder

Curated by ChEMBL
LigandPNGBDBM50514137(CHEMBL4455524)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK293 cells assessed as reduction in R848-induced NFkappaB production incubated for 16 hrs by quanti-blue SEAP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed