BDBM50514148 CHEMBL4475557

SMILES Fc1cccc(Cl)c1C(=O)Nc1ccc(Oc2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1

InChI Key InChIKey=ZBTXLIOBUPNJDF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50514148   

TargetToll-like receptor 8(Human)
University of Colorado Boulder

Curated by ChEMBL
LigandPNGBDBM50514148(CHEMBL4475557)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK293 cells assessed as reduction in R848-induced NFkappaB production incubated for 16 hrs by quanti-blue SEAP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
University of Colorado Boulder

Curated by ChEMBL
LigandPNGBDBM50514148(CHEMBL4475557)
Affinity DataIC50: 2.88E+3nMAssay Description:Inhibition of human TLR7 expressed in HEK293 cells assessed as reduction in R848-induced NFkappaB production incubated for 16 hrs by quanti-blue SEAP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed