BDBM50514153 CHEMBL4469304

SMILES Fc1cc(Oc2ccc(NC(=O)c3c(F)cccc3Cl)cc2)cc(c1)C(F)(F)F

InChI Key InChIKey=QCQWYTGFZBOUAP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50514153   

TargetToll-like receptor 8(Human)
University of Colorado Boulder

Curated by ChEMBL
LigandPNGBDBM50514153(CHEMBL4469304)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK293 cells assessed as reduction in R848-induced NFkappaB production incubated for 16 hrs by quanti-blue SEAP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed