BDBM50514509 CHEMBL4475369

SMILES COc1cc(C)c(NC(=O)c2cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc2Nc2ccccc2NC(=O)C=C)cc1OC

InChI Key InChIKey=QXUDOYJGRSEHPZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50514509   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50514509(CHEMBL4475369 | US12365664, Compound 23)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of recombinant human His-tagged full length SRC expressed in baculovirus expression system using tyrosine-2 peptide as substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50514509(CHEMBL4475369 | US12365664, Compound 23)
Affinity DataIC50: 5.50E+3nMAssay Description:All examples described herein possessed activity in a commercial assay from SelectScreen Kinase Profiling Services in ThermoFisher Scientific company...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50514509(CHEMBL4475369 | US12365664, Compound 23)
Affinity DataIC50: 6.71E+3nMAssay Description:Inhibition of recombinant human His-tagged FGFR1 (308 to 731 residues) expressed in baculovirus expression system using tyrosine-4 peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed