BDBM50514528 CHEMBL4537568

SMILES CN1CCN(CC1)c1ccc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)c(Nc3ccccc3NS(=O)(=O)C=C)n2)cc1

InChI Key InChIKey=GYFXWBJQCMGYGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50514528   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50514528(CHEMBL4537568 | US12365664, Compound 52)
Affinity DataIC50: 5.5nMAssay Description:All examples described herein possessed activity in a commercial assay from SelectScreen Kinase Profiling Services in ThermoFisher Scientific company...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50514528(CHEMBL4537568 | US12365664, Compound 52)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human His-tagged full length SRC expressed in baculovirus expression system using tyrosine-2 peptide as substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed