BDBM50514596 CHEMBL4455710

SMILES COC(=O)c1ccccc1-n1cc(CNC(=O)c2cnc3ccc(cn23)-c2cnc(OC)c(NS(=O)(=O)c3ccc(F)cc3F)c2)nn1

InChI Key InChIKey=GDKVKIGRSSLHPJ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50514596   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
East China Normal University

Curated by ChEMBL

LigandBDBM50514596(CHEMBL4455710)Copy SMILESCopy InChI

Affinity DataIC50: 0.170nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/21/2021
Entry Details Article
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