BDBM50514993 CHEMBL4435374

SMILES Nc1nc2[nH]c(CCNC(=O)c3ccc(cc3)C(=O)NCc3cccnc3)cc2c(=O)[nH]1

InChI Key InChIKey=XVEHMXAYEWAUAY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50514993   

TargetDihydrofolate reductase(Human)
Hebei Medical University

Curated by ChEMBL
LigandPNGBDBM50514993(CHEMBL4435374)
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant human DHFR using dihydrofolic acid as substrate in presence of NADPH after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed