BDBM50515051 CHEMBL4439431

SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]5(O)CC\C2=N\OCC(=O)NCCCCCCNC(=O)CCCCCn1cc(C(=O)c2cccc4ccccc24)c2ccccc12)ccc3OC

InChI Key

Data  5 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50515051   

TargetCannabinoid receptor 1(Rat)
Biological Research Centre of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50515051(CHEMBL4439431)
Affinity DataEC50:  452nMAssay Description:Agonist activity at CB1R in Wistar rat brain membranes in presence of rimonabant after 60 mins by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Centre of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50515051(CHEMBL4439431)
Affinity DataEC50:  397nMAssay Description:Agonist activity at MOR in Wistar rat brain membranes in presence of naloxone after 60 mins by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Rat)
Biological Research Centre of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50515051(CHEMBL4439431)
Affinity DataEC50:  340nMAssay Description:Agonist activity at CB2R in Wistar rat brain membranes in presence of AM630 after 60 mins by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCannabinoid receptor 1/2(Rat)
Biological Research Centre of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50515051(CHEMBL4439431)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]WIN-55,212-2 from CB1R/CB2R in Wistar rat brain membranes after 60 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Biological Research Centre of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50515051(CHEMBL4439431)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes after 60 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCannabinoid receptor 1/2(Rat)
Biological Research Centre of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50515051(CHEMBL4439431)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]JWH-018 from CB1R/CB2R in Wistar rat brain membranes after 60 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Biological Research Centre of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50515051(CHEMBL4439431)
Affinity DataKi:  172nMAssay Description:Displacement of [3H]HS-665 from KOR in guinea pig brain membranes after 60 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Biological Research Centre of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50515051(CHEMBL4439431)
Affinity DataKi:  263nMAssay Description:Displacement of [3H]Ile5,6-deltorphin-2 from DOR in Wistar rat brain membranes after 60 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed