BDBM50515316 CHEMBL4513885

SMILES Cc1cccc(n1)-c1nn(CC(=S)Nc2cccc(c2)C#N)cc1-c1cc2cnccc2s1

InChI Key InChIKey=UWGGOJHRAMGQCH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50515316   

TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50515316(CHEMBL4513885)
Affinity DataIC50: 78nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in Sf9 insect cells using casein as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50515316(CHEMBL4513885)
Affinity DataIC50: 9.46E+3nMAssay Description:Inhibition of human recombinant untagged p38alpha expressed in Escherichia coli using ATF2 as substrate incubated for 60 mins in presence of [33P]-AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed