BDBM50515566 CHEMBL4475538

SMILES CN1c2ccccc2Sc2cc(\C=C3\SC(=S)N(CC(=O)OCC4COC(C)(C)O4)C3=O)ccc12

InChI Key InChIKey=IPHJRUZANDHSCX-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50515566   

TargetAmyloid-beta precursor protein(Human)
Guangdong University of Technology

Curated by ChEMBL
LigandPNGBDBM50515566(CHEMBL4475538)
Affinity DataKd:  25nMAssay Description:Binding affinity to amyloid beta 1 to 42 (unknown origin) in PBS buffer at pH 7.4 assessed as binding constant by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Guangdong University of Technology

Curated by ChEMBL
LigandPNGBDBM50515566(CHEMBL4475538)
Affinity DataIC50: 60nMAssay Description:Inhibition of amyloid beta 1 to 42 aggregation in human SH-SY5Y cells incubated for 48 hrs by fluorescence microscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed