BDBM50515632 CHEMBL4436445

SMILES CC(C)(C)NC(=O)C(NCc1ccc(OCc2ccccc2Br)cc1)c1c([nH]c2cc(Cl)ccc12)C(O)=O

InChI Key InChIKey=NNPRLGPHUYKKSB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50515632   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50515632(CHEMBL4436445)
Affinity DataKi:  1.85E+3nMAssay Description:Displacement of 5'FAM-LTFEHYWAQLTS from human recombinant N-terminal domain of MDM2 (1 to 118 residues) expressed in Escherichia coli BL21 (DE3) cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed