BDBM50515967 CHEMBL4439071

SMILES [H][C@@]12[#6]-[#6@@H](-[#8])[C@@]3([H])[C@@]4([#6])[#6]-[#6]-[#6@@H](-[#8])-[#6@@H](-[#6])[C@]4([H])[#6]-[#6][C@]3([#6])[C@@]1([#6])[#6]-[#6@H](-[#8]-[#6](-[#6])=O)\[#6]2=[#6](\[#6]-[#6]\[#6]=[#6](/[#6])-[#6])-[#6](=O)-[#8]-[#6]-c1ccccc1

InChI Key InChIKey=QFALWWDHMQCEGC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50515967   

TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50515967(CHEMBL4439071)
Affinity DataIC50: 7nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50515967(CHEMBL4439071)
Affinity DataIC50: 17nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50515967(CHEMBL4439071)
Affinity DataIC50: 92nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KBV cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50515967(CHEMBL4439071)
Affinity DataIC50: 144nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KBV cells assessed as potentiation of vincristine-induced cytotoxicity by measuring vincristi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50515967(CHEMBL4439071)
Affinity DataIC50: 1.62E+4nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KBV cells assessed as potentiation of irinotecan-induced cytotoxicity by measuring irinotecan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50515967(CHEMBL4439071)
Affinity DataIC50: 3.73E+4nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KBV cells assessed as potentiation of irinotecan-induced cytotoxicity by measuring irinotecan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed