BDBM50515986 CHEMBL4553527

SMILES COc1ccc2nc(C)cc(N\N=C\c3c[nH]cn3)c2c1

InChI Key InChIKey=WCZXPOPEPIBDAW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50515986   

TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50515986(CHEMBL4553527)
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human NQO2 expressed in Escherichia coli using DCPIP as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50515986(CHEMBL4553527)
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of NQO2 in human SKOV3 cells assessed as reduction in cell viability in presence of 1 uM CB1954 and EPR incubated for 24 hrs measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50515986(CHEMBL4553527)
Affinity DataIC50: 3.87E+4nMAssay Description:Inhibition of recombinant human NQO1 expressed in Escherichia coli using DCPIP as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed