BDBM50516021 CHEMBL4548212

SMILES CNC(=O)Nc1ccc(cc1)-c1ncc2NC(=O)C3COCCN3c2n1

InChI Key InChIKey=FUBIRECNIIHURQ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50516021   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Takeda California

Curated by ChEMBL

LigandBDBM50516021(CHEMBL4548212)Copy SMILESCopy InChI

Affinity DataIC50: 32nMAssay Description:Inhibition of PI3K alpha (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/22/2021
Entry Details Article
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TargetSerine/threonine-protein kinase mTOR(Human)
Takeda California

Curated by ChEMBL

LigandBDBM50516021(CHEMBL4548212)Copy SMILESCopy InChI

Affinity DataIC50: 316nMAssay Description:Inhibition of human mTOR measured after 30 mins in presence of ATP by Lanthascreen TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/22/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL