BDBM50516059 CHEMBL4435546

SMILES O=C(Oc1cccc(c1)N1CCS(=O)(=O)CC1)N1CCC(CC1)c1ccc(cc1)N1CCC1

InChI Key InChIKey=VMERACSLFCLHSV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50516059   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50516059(CHEMBL4435546)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of rat recombinant His/GST-tagged FAAH expressed in Escherichia coli cells using AAMCA as substrate incubated for 15 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50516059(CHEMBL4435546)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human recombinant MBP-tagged FAAH expressed in Escherichia coli cells using AAMCA as substrate incubated for 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50516059(CHEMBL4435546)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant His-tagged MGL expressed in Escherichia coli BL21 DE3 cells using AHMMCE as substrate preincubated with enzyme for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed