BDBM50516348 CHEMBL4442173

SMILES COc1cc(NC(=O)c2coc3ccccc3c2=O)c(cc1OC)-c1nnn(n1)-c1ccc(CCN2CCc3ccccc3C2)cc1

InChI Key InChIKey=MTSTVZWVQAZPCW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50516348   

TargetATP-dependent translocase ABCB1(Human)
Henan University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50516348(CHEMBL4442173)
Affinity DataIC50: 35nMAssay Description:Inhibition of Pgp (unknown origin) expressed in MDCK cells assessed as reduction in paclitaxel transportMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed