BDBM50516424 CHEMBL4575160

SMILES [H][C@@]12C[C@@]1(CN(C2)c1nnc(CC#N)n1-c1ccc(OC)nc1)c1ccc(F)cc1Cl

InChI Key InChIKey=DDPIHYVFODKELW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50516424   

TargetOxytocin receptor(Human)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50516424(CHEMBL4575160)
Affinity DataIC50: 235nMAssay Description:Antagonist activity at human OTR expressed in HEK293 cells assessed as decrease in calcium flux measured after 10 mins in presence of vasopressin by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50516424(CHEMBL4575160)
Affinity DataIC50: 769nMAssay Description:Antagonist activity at human vasopressin V1A receptor expressed in HEK293 cells assessed as decrease in vasopressin-stimulated calcium flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetVasopressin V1b receptor(Human)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50516424(CHEMBL4575160)
Affinity DataIC50: 4.44E+4nMAssay Description:Antagonist activity at human vasopressin V1B receptor expressed in HEK293 cells assessed as decrease in vasopressin-stimulated calcium flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed