BDBM50516497 CHEMBL4592597

SMILES Cc1cc2ccnc(Nc3ccc(Oc4ccnc(N)c4Cl)c(F)c3)c2c(=O)n1-c1ccc(Cl)cc1

InChI Key InChIKey=BRFFOZKQXZVVQO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50516497   

TargetHepatocyte growth factor receptor(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50516497(CHEMBL4592597)
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant His-tagged cMET cytoplasmic domain expressed in baculovirus expression system using biotin as substrate preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50516497(CHEMBL4592597)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human His-tagged VEGFR2 cytoplasmic domain expressed in baculovirus expression system using biotin as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed