BDBM50516538 CHEMBL4559652

SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CCSC)NC(=O)OCc1ccccc1

InChI Key InChIKey=RHMRGXIFCHMUBP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50516538   

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50516538(CHEMBL4559652)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human COX-2 assessed as reduction in prostaglandin production preincubated for 10 mins followed by arachidonic acid additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
TBA

Curated by ChEMBL
LigandPNGBDBM50516538(CHEMBL4559652)
Affinity DataIC50: 500nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in prostaglandin production preincubated for 10 mins followed by arachidonic acid addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed