BDBM50516644 CHEMBL4563021

SMILES OC(CC1c2cc(F)ccc2-c2cncn12)C1CCCCC1

InChI Key InChIKey=PKEXUVAGVPPMGW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50516644   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50516644(CHEMBL4563021)
Affinity DataEC50:  340nMAssay Description:Inhibition of recombinant human IDO1 expressed in T-REx-293 cells assessed as reduction in kynurenine level measured after 16 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50516644(CHEMBL4563021)
Affinity DataIC50: 420nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed