BDBM50516904 CHEMBL1433758

SMILES Cc1cccc(Nc2ncnc3onc(-c4ccc(F)cc4)c23)c1C

InChI Key InChIKey=UVTPIEBCKYUPPY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50516904   

TargetCystic fibrosis transmembrane conductance regulator(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50516904(CHEMBL1433758)
Affinity DataIC50: 3.90E+3nMAssay Description:Corrector activity at human CFTR F508del mutant expressed in rat FRT cells iodide influx incubated for 16 to 20 hrs followed by compound wash out and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed