BDBM50516961 CHEMBL4471734

SMILES Clc1cc(Cl)c(c(Cl)c1)-n1cc(Cn2ncc3c2c2ccccc2oc3=O)nn1

InChI Key InChIKey=ZRKPJYUBXDGYDK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50516961   

TargetCholinesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50516961(CHEMBL4471734)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50516961(CHEMBL4471734)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of 5-lipoxygenase (unknown origin) incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50516961(CHEMBL4471734)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of BuChE (unknown origin) using butyrylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed