BDBM50517081 CHEMBL4462083

SMILES NS(=O)(=O)c1ccc(OCCCNC(=O)c2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)cc1

InChI Key InChIKey=LERLZACAVSWHNG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50517081   

TargetCarbonic anhydrase 9(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50517081(CHEMBL4462083)
Affinity DataKi:  188nMAssay Description:Inhibition of recombinant human CA9 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50517081(CHEMBL4462083)
Affinity DataKi:  363nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50517081(CHEMBL4462083)
Affinity DataKi:  933nMAssay Description:Inhibition of recombinant human CA2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50517081(CHEMBL4462083)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of recombinant human CA1 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed