BDBM50517100 CHEMBL4450841

SMILES CCCS(=O)(=O)CCc1cc(-c2ccc(cc2)S(C)(=O)=O)n(c1C)-c1ccccc1

InChI Key InChIKey=KOURFNDTLOGJGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50517100   

TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50517100(CHEMBL4450841)
Affinity DataIC50: 34nMAssay Description:Inhibition of COX-2 in LPS-induced mouse J774 cells assessed as inhibition of PEG2 production after 24 hrs by radioimmuno assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50517100(CHEMBL4450841)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX-1 in mouse J774 cells assessed as inhibition of PEG2 production using arachidonic acid as substrate pretreated for 15 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed