BDBM50517610 CHEMBL4545073
SMILES COC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)c1cnc(C)s1)C(=O)N[C@@H](Cc1ccc(CN)cc1)\C=C\S(C)(=O)=O
InChI Key InChIKey=LMXBCHXXOUDFDR-UHFFFAOYSA-N
Data 14 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50517610
TargetProteasome subunit beta type-2(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-10(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 20S immunoproteasome beta 2 (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-10(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of 20S immunoproteasome beta 2 in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity in human RPMI8226 cell lysates after 1 hr by coomassie brilliant blue staining...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-8(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 20S immunoproteasome beta 5 in human RPMI8226 cell lysates after 1 hr by coomassie brilliant blue staining-based fluorescence assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 20S constitutive proteasome beta 5 chymotrypsin-like activity in human RPMI8226 cell lysates after 1 hr by coomassie brilliant blue sta...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-10(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 20S immunoproteasome beta 2 in human RPMI8226 cell lysates after 1 hr by coomassie brilliant blue staining-based fluorescence assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 20S constitutive proteasome beta 1 caspase-like activity in human RPMI8226 cell lysates after 1 hr by coomassie brilliant blue staining...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-9(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 20S immunoproteasome beta 1 in human RPMI8226 cell lysates after 1 hr by coomassie brilliant blue staining-based fluorescence assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 4.53E+4nMAssay Description:Inhibition of 20S constitutive proteasome beta 5 chymotrypsin-like activity in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-8(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 5.71E+4nMAssay Description:Inhibition of 20S immunoproteasome beta 5 in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-9(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 20S immunoproteasome beta 1 in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Human)
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute of Chemistry and Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 20S constitutive proteasome beta 1 caspase-like activity in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair