BDBM50517663 CHEMBL4583637

SMILES CS(=O)(=O)c1ncccc1CNc1ncc(C#N)c(NCC23CC4CC(C2)C(NC[C@H]2CC[C@H](O)CC2)C(C4)C3)n1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50517663   

TargetProtein kinase C theta type(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50517663(CHEMBL4583637)
Affinity DataIC50: 140nMAssay Description:Inhibition of PKCtheta in human Jurkat cells assessed as reduction in IL2 production after 14 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed