BDBM50517680 CHEMBL4533143

SMILES [H][C@]1(CC[C@@H](CC1)Nc1ncnc2sc(CC(F)(F)F)cc12)N[C@@H]1C[C@H]1c1ccc(F)c(F)c1

InChI Key InChIKey=WDIBYDGOTYSGMR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50517680   

TargetLysine-specific histone demethylase 1A(Human)
Liaoning Shihua University

Curated by ChEMBL
LigandPNGBDBM50517680(CHEMBL4533143)
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human LSD1 (172 to 852 residues) using biotin-labelled H3K4me2 (1 to 24 residues) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Liaoning Shihua University

Curated by ChEMBL
LigandPNGBDBM50517680(CHEMBL4533143)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of MAOB (unknown origin) by Promega MAO-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Liaoning Shihua University

Curated by ChEMBL
LigandPNGBDBM50517680(CHEMBL4533143)
Affinity DataIC50: 4.09E+4nMAssay Description:Inhibition of MAOA (unknown origin) by Promega MAO-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed