BDBM50517806 CHEMBL4541720

SMILES CC(C)CC(NC(=O)c1ccc(cc1)-c1ccc(cc1)S(C)(=O)=O)C(=O)N(C)N(C)C#N

InChI Key InChIKey=XHBRHGRXSUUCGR-UHFFFAOYSA-N

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50517806   

TargetCathepsin K(Human)
Jilin University

Curated by ChEMBL
LigandPNGBDBM50517806(CHEMBL4541720)
Affinity DataKi:  1.10nMAssay Description:Inhibition of recombinant His-tagged human cathepsin K expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCathepsin K(Human)
Jilin University

Curated by ChEMBL
LigandPNGBDBM50517806(CHEMBL4541720)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant His-tagged human cathepsin K expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Jilin University

Curated by ChEMBL
LigandPNGBDBM50517806(CHEMBL4541720)
Affinity DataKi:  195nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCathepsin S(Human)
Jilin University

Curated by ChEMBL
LigandPNGBDBM50517806(CHEMBL4541720)
Affinity DataKi:  239nMAssay Description:Inhibition of recombinant human cathepsin S expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCathepsin S(Human)
Jilin University

Curated by ChEMBL
LigandPNGBDBM50517806(CHEMBL4541720)
Affinity DataIC50: 332nMAssay Description:Inhibition of recombinant human cathepsin S expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCathepsin B(Human)
Jilin University

Curated by ChEMBL
LigandPNGBDBM50517806(CHEMBL4541720)
Affinity DataKi:  909nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCathepsin B(Human)
Jilin University

Curated by ChEMBL
LigandPNGBDBM50517806(CHEMBL4541720)
Affinity DataIC50: 915nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Jilin University

Curated by ChEMBL
LigandPNGBDBM50517806(CHEMBL4541720)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed