BDBM50518027 CHEMBL4550815::US11498896, Compound 1

SMILES CC1(CCN(CCOc2ccccc2)C1)Oc1ccc(Cl)cc1

InChI Key InChIKey=SHXNMYNFGRHTQN-UHFFFAOYSA-N

Data  1 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50518027   

TargetD(2) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518027(CHEMBL4550815 | US11498896, Compound 1)
Affinity DataEC50:  120nMAssay Description:Agonist activity at dopamine D2long receptor (unknown origin) assessed as increased in cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518027(CHEMBL4550815 | US11498896, Compound 1)
Affinity DataEC50:  2.14E+3nMAssay Description:Antagonist activity at dopamine D2long receptor (unknown origin) assessed as inhibition of agonist-induced beta-arrestin recruitmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518027(CHEMBL4550815 | US11498896, Compound 1)
Affinity DataKi:  5.50E+3nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518027(CHEMBL4550815 | US11498896, Compound 1)
Affinity DataEC50: >3.00E+4nMAssay Description:Antagonist activity at dopamine D2long receptor (unknown origin) assessed as inhibition of agonist-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518027(CHEMBL4550815 | US11498896, Compound 1)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at dopamine D2long receptor (unknown origin) assessed as increase in beta-arrestin recruitmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed