BDBM50518155 CHEMBL4455740

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

InChI Key InChIKey=FZAYLBZSNRRXLG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50518155   

TargetProteasome subunit beta type-5(Human)
University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50518155(CHEMBL4455740)
Affinity DataIC50: 95nMAssay Description:Negative allosteric modulation of SDS-activated human erythrocytes 20S proteasome chymotrypsin like activity using Suc-LLVY-AMC as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50518155(CHEMBL4455740)
Affinity DataIC50: 1.60E+3nMAssay Description:Negative allosteric modulation of 1 uM Rpt5-activated human erythrocytes 20S proteasome chymotrypsin like activity using Suc-LLVY-AMC as substrate me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50518155(CHEMBL4455740)
Affinity DataIC50: 1.90E+3nMAssay Description:Negative allosteric modulation of 10 uM Rpt5-activated human erythrocytes 20S proteasome chymotrypsin like activity using Suc-LLVY-AMC as substrate m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed