BDBM50518351 CHEMBL4470500

SMILES NC1=CC(N)=C2C=CC(=O)N=C2C1=O

InChI Key InChIKey=MNCJAIOYOIRYJW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50518351   

TargetTyrosyl-DNA phosphodiesterase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50518351(CHEMBL4470500)
Affinity DataIC50: 40nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50518351(CHEMBL4470500)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant human TDP2 using T5PNP as substrate preincubated for 10 mins followed by substrate addition and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50518351(CHEMBL4470500)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of TDP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed