BDBM50518404 CHEMBL4455896

SMILES Nc1ncnc2c(csc12)C(=O)Nc1cccc2n(Cc3cccnc3)nc(Br)c12

InChI Key InChIKey=RNSPJNIKRAJKOU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50518404   

TargetCytochrome P450 1A2(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518404(CHEMBL4455896)
Affinity DataIC50: 250nMAssay Description:Inhibition of CYP1A2 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518404(CHEMBL4455896)
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518404(CHEMBL4455896)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518404(CHEMBL4455896)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518404(CHEMBL4455896)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518404(CHEMBL4455896)
Affinity DataIC50: 310nMAssay Description:Inhibition of CYP3A4 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed