BDBM50518469 CHEMBL4518180

SMILES [H][C@]12CCC[C@H](N3CCCC3)[C@@]1([H])N(CCN2C(=O)Cn1cc(CCCF)nn1)C(=O)Cc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=XPPNLEJFCXIJTB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50518469   

TargetKappa-type opioid receptor(Guinea pig)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50518469(CHEMBL4518180)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]U-69,593 from KOR in guinea pig brain membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50518469(CHEMBL4518180)
Affinity DataKi:  425nMAssay Description:Displacement of [3H]DPDPE from DOR in Sprague-Dawley rat brain membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50518469(CHEMBL4518180)
Affinity DataKi:  947nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed