BDBM50518764 CHEMBL4462303

SMILES COc1cc(OC)c2nnc3n(C)nc(-c4ccnc(C)c4)c3c2c1

InChI Key InChIKey=PJTWMFJUPLYADV-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50518764   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Abbvie Deutschland

Curated by ChEMBL

LigandBDBM50518764(CHEMBL4462303)Copy SMILESCopy InChI

Affinity DataIC50: 105nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/23/2021
Entry Details Article
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Abbvie Deutschland

Curated by ChEMBL

LigandBDBM50518764(CHEMBL4462303)Copy SMILESCopy InChI

Affinity DataIC50: 6.13E+3nMAssay Description:Inhibition of human full-length PDE4D2 expressed in Sf9 insect cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/23/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL